Ranking of the best blood thinners for 2020

Thickening of blood can serve as the beginning for such serious diseases as varicose veins, thrombosis, thrombophlebitis, atherosclerosis, heart attack, stroke, as well as other malfunctions of the cardiovascular system. The mytop.techinfus.com/en/ team brings you a list of the best blood thinners to help prevent a number of diseases. The survey included medicines that received the highest customer ratings. During the selection, special attention was paid to the effectiveness of drugs, their cost, safety and ease of use.

The best blood thinners of the antiplatelet group

The action of antiplatelet agents is aimed at preventing platelets from sticking together. Medicines of this group are used in the treatment of cardiac diseases such as the consequences of ischemic stroke, angina pectoris, peripheral arterial disease, the prevention of heart attack and the treatment of its consequences, as well as in bypassing and stenting of the coronary arteries.

Deplatt

The action of this drug is aimed at preventing peripheral arterial occlusions, ischemic strokes, atrial fibrillation, and myocardial infarction. Deplatt's active ingredient is clopidogrel. In medical practice, its combination with acetylsalicylic acid is often used. The interaction of these two substances is used to prevent thrombotic complications in the acute form of coronary syndrome. Deplatte comes in pill form with a dosage of 75 mg. Usually, the following regimen is prescribed: 1 tablet per day, regardless of food intake. The average cost of this drug is 439 rubles.

• Excellent communication with blood plasma proteins - 98-94%;
• Ease of use;
• Maximum concentration time - only 45 minutes;
• Acceptable cost.

• The minimum age for application is 18 years.

Cardiomagnet

Cardiomagnet is a combination of two substances - acetylsalicylic acid and magnesium hydroxide. The mechanism of action of aspirin is aimed at blocking thromboxone synthesis and suppressing platelet aggregation. Magnesium hydroxide prevents the aggressive effects of acetylsalicylic acid on the mucous membranes of the digestive system.

This drug is used as protection against re-infarction, for the prevention of cardiovascular diseases, thrombosis and thromboembolism, as well as unstable angina pectoris. Cardiomagnet has several forms of release: 20 and 100 tablets. On average, the cost of this product is 116 rubles for 30 tablets. It comes without a prescription.

• Affordable price;
• Few contraindications;
• Prevalence;
• Efficiency.

• Frequency of side effects.

Egithrombus

Egithrombus is used to prevent complications in ischemic stroke, occlusive arterial disease, myocardial infarction, acute coronary syndrome, atrial fibrillation, unstable angina pectoris. Clopidogrel hydrogen sulfate is used as an active ingredient in this preparation. The advantage of Egithrombus is its excellent connection with plasma proteins, which is 94-98%.

Inhibition of association by platelet occurs within 2 hours after using this drug. The maximum effectiveness appears after 4-7 days. This antiplatelet agent is available as a film-coated tablet. Their dosage is 75 mg. Release form - 14 and 28 pcs. packaged. The duration of therapy depends on the severity of the disease. The minimum period is several days, the maximum is six months. 75% of the drug is excreted through the intestines, 46% through the kidneys. The average price of Egitromba is 883 rubles per pack with 28 tablets.

• High bioavailability;
• Convenient dosage regimen - 1 tablet per day;
• A small number of contraindications;
• Greater efficiency.

• High price;
• Cannot be used by children under 18 years of age.

Curantil

Curantil is available in packs of 40 (75 mg), 100 (25 mg) and 120 (25 mg) tablets. The active component of this agent is dipyridamole. It has a wide range of effects on the body. The drug perfectly copes with improving placental and venous outflow, lowering blood pressure, vasodilatation, normalizing the rheological properties of blood, reducing the resistance of cerebral vessels (especially important for people after 40 years). In addition, Curantil has proven itself as an immunomodulator.

For the prevention of respiratory diseases and influenza, 50 mg of the substance is prescribed once a week for 4 weeks. For the prevention of other diseases, the dose is increased to 75-600 mg per day, depending on the severity of the case. The tablets should be taken in the morning on an empty stomach with a small amount of liquid. On average, the price for a pack of 120 tablets is 590 rubles.

• Acceptable cost;
• Extensive scope of application;
• Suitable for lactating and pregnant women;
• The minimum number of contraindications;
• Convenient form of release.

• Not found.

Trental

The main active substance of Trental is pentoxifylline. Its advantage is the ability to thin the blood in 2 ways. In addition to reducing platelet adhesion, the substance also affects erythrocytes, improving their ability to tolerate deformation. Also, the use of this drug helps to reduce the concentration of fibrinogen, activity and adhesion of leukocytes.

Trental is used for poor circulation in the choroid and retina of the eyes, cerebrovascular accidents, degenerative changes, diabetic genesis, otosclerosis, occlusive disease and trophic disorders. It is also often used to treat chronic peripheral circulatory disorders in the elderly. Packages are available in 400 (400 mg), 60 (100 mg) and 20 (400 mg) tablets. You can also purchase a concentrate for self-preparation of the solution. The average price of Trental is 496 rubles for 60 tablets.

• Good price;
• High bioavailability;
• Convenient form of release;
• The optimum ratio of price and quality;
• Complex action.

• There are many contraindications.

Acetylsalicylic acid

Acetylsalicylic acid is a budget non-prescription antiplatelet agent that is highly effective not only in preventing blood clots. This substance is used to treat inflammation, reduce fever, and relieve pain. It is often used for fever, Kawasaki disease, arthritis, pericarditis, headache, varicose veins, cardiovascular diseases.Also, this medication has shown itself well in the prevention of heart attacks and strokes.

This drug is supplied in packs of 10, 20, 30 and 40 tablets, where the amount of active ingredient is 500 mg. There are also packs of 30 and 20 tablets with an amount of 100 and 300 mg. The dosage of aspirin depends on the type of disease. The minimum amount of substance per dose is 0.1 g, the maximum is 3 g. On average, the cost for 20 tablets is 15 rubles.

Acetylsalicylic acid is included in the list of important medicines of the Russian Federation and the World Health Organization.

• Low price;
• Proven safety;
• A wide range of therapeutic actions;
• Fast results;
• Lots of positive reviews.

• A considerable number of contraindications.

The best blood thinners of the anticoagulant group

Anticoagulants prevent blood clots from forming by affecting proteins in the blood. These funds are used in cardiological practice in the treatment of heart failure, heart rhythm disturbances, infective endocarditis, mitral stenosis, thromboembolism, heart valve replacement and thrombosis.

Fraxiparine

The active ingredient of Fraxiparine is nadroparin calcium obtained by depolymerization from ordinary heparin. The low molecular weight substance is highly effective in preventing the formation of blood clots and inhibiting the activity of the blood coagulation system. This is possible due to its high ability to bind to blood plasma protein. The advantage of this substance is its almost complete bioavailability - about 98% and the minimum absorption time - 3-5 hours.

This drug shows excellent results in the prevention and treatment of myocardial infarction, unstable angina pectoris, thromboembolism, blood coagulation during hemodialysis. Fraxiparine is supplied as an injection solution. There are several forms of release: ampoules of 0.3, 0.4, 0.6 and 0.8 and 1 ml. The average price of this medication is 2,540 rubles for 10 syringes of 0.3 ml.

Note! The use of Fraxiparine implies constant monitoring of the platelet count, since there is a high probability of developing heparin-induced thrombocytopenia.

• High efficiency;
• Excellent bioavailability;
• Several forms of release.

• High price.

Warfarin

Warfarin was registered in 1948 but was originally used as a rodent poison. As a therapeutic anticoagulant, the drug began to be used in 1954, after a series of studies. The medicine is available in tablets that contain 2.5 mg of the active ingredient - sodium warfarin. The minimum number of tablets in a package is 30 pieces, the maximum is 150 pieces. Warfarin is dispensed by prescription.

The mechanism of action of this medication is aimed at suppressing the synthesis of proteins S, C and vitamin K-dependent factors of blood coagulation in the liver. The rheological properties of the blood improve after 3-5 days of use. It is necessary to take Warfarin 1 time per day and at the same time. The starting dose is one to two tablets. The dose may be increased depending on the severity of the disease. The drug is excreted by the kidneys. Average cost: 88 rubles per 100 tablets.

• Affordable price;
• Low likelihood of side effects;
• Ease of use;
• Availability at any pharmacy;
• High efficiency.

• Many contraindications;
• Incompatibility with a large number of medications.

Pradaxa

Pradaxa is a new generation prescription drug that does not possess pharmacological activity, but belongs to low molecular weight prodrugs. Its active component, dabigatran etexilate, has an anticoagulant effect within 2-3 hours after ingestion. The prodrug is excreted through the gastrointestinal tract (6%) and kidneys (85%).

Pradaxa is available in the form of oblong, hard capsules, the amount of the substance of which is 75, 110 or 150 mg.Dosage regimen - 2-3 times a day, 1-2 capsules. This anticoagulant is on the list of essential drugs of the World Health Organization, which confirms its effectiveness and safety. The average cost of Pradax is 1,762 rubles, for 30 capsules with a dosage of 75 mg.

A prodrug is a chemically altered form of a drug or compound that is converted into a pharmacologically active drug directly in the human body.

• High bioavailability;
• Fast absorption;
• No need for regular blood tests;
• Safe composition;
• Efficiency;
• A small number of contraindications.

• High price.

Clexane

The active ingredient in Clexane is sodium enoxaparin. The drug is available in the form of a solution. For ease of use, the solution is placed in disposable syringes with a volume of 0.2, 0.4, 0.6, 0.8, 1 ml. Its advantage is almost 100% bioavailability, since the solution is injected directly under the skin, in the shoulder or abdomen area. The maximum activity of the drug in the blood plasma is noted after 3-4 hours. Clexane is excreted by the kidneys.

This anticoagulant is used for the prevention and treatment of venous thrombosis and embolism, and is also often used in acute infarction. Prescription drug, recommended for inpatient treatment. If it is necessary to administer the solution at home, a step-by-step instruction is attached in the package. Usually, the course of admission is from 3 to 7 days. On average, the cost of a medication is 607 rubles for a volume of 0.6 ml.

• High-speed performance;
• Excellent bioavailability;
• Therapy for angina pectoris and acute heart attack;
• Minimum side effects;
• A small number of contraindications.

• Very high price;
• One form of release.

Plavix

Plavix is ​​another prodrug. Its active ingredient is clopidogrel hydrogen sulfate. The drug is very popular in the treatment of the consequences of strokes and myocardial infarction. It is also successfully used in acute coronary syndrome and atherosclerosis.

Plavix is ​​available in packs of 10, 28 and 100 tablets, the dosage of the active ingredient in 1 tablet is 75 or 100 mg. The dosage regimen is simple: 75 mg once a day. The drug takes effect 2 hours after taking it. The drug is excreted through the intestines (46%) and through the kidneys (50%). The average cost of a pack is 3,010 rubles (100 tablets, 75 mg)

• High efficiency;
• Several forms of release;
• Complex action;
• Application does not depend on meal time.

• High price.

Wessel

Wessel's advantage is naturalness. Its active component, sulodexide, is a compound of a heparin-like fraction (80%) and dermatan sulfate - 20%. Dermatan sulfate is isolated from the mucous membrane of the porcine intestine. The medicine is suitable for thinning blood and strengthening the walls of blood vessels. Also used for discirculatory encephalopathy, acute ischemic stroke, peripheral arterial lesions, microangiopathy.

The dosage form of this agent is a light yellow solution in ampoules or capsules. Usually, the treatment is prescribed as follows: intramuscular or intravenous administration of the solution once a day for 15-20 days, then taking 1-2 capsules a day for 30-40 days. Wessel works within 15 minutes after application. The drug is excreted by the kidneys. On average, the cost of the drug is 2,747 rubles.

• Versatility;
• Possibility of use during pregnancy;
• Good tolerance;
• Not addictive;
• High efficiency;
• Safe composition.

• Expensive.

Where can you buy the drugs presented in the rating?

All of the products presented in this review can be ordered online from online pharmacies or offline pharmaceutical outlets.

Conclusion

The review presented the best, most effective and safest blood thinners, which were selected based on positive consumer reviews. Before buying any of the presented funds, you must definitely consult a specialist!